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The Cardiovascular Medical Research and Education Fund

Announcements:

During 2010, in recognition of the potential value of the biological materials and information gathered by PHBI, the National Institutes of Health (“NIH”) announced its intention to make “RO3” grants to utilize “available human biospecimens collected by the Pulmonary Hypertension Breakthrough Initiative (PHBI) ... to investigate mechanistic research questions in lung vascular biology, including validating hypotheses of pulmonary arterial hypertension (PAH).

NIH R03 collaboration with the PHB: 

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News:

The CMREF has approved a grant for $950,000 to Circulite, Inc for the development of a right ventricular assist device to be developed as a treatment of advanced pulmonary hypertension refractory to medical therapy. In the current scheme of medical treatments, the only treatment for patients who have failed approved medical therapies, including intravenous prostacyclins, is lung transplantation. However, due to the strict criteria for listing patients, and the severe shortage of donor lungs, the majority of these patients will never be transplanted. It is the hope of Circulite that the right ventricular assist device will fill this unmet medical need.

Request for Proposal:
The Cardiovascular Medical Research and Education Fund is seeking proposals from qualified academic medical centers with the ability to coordinate and conduct a clinical study evaluating right ventricular function in patients with pulmonary hypertension, its adaptive and maladaptive responses, and the effects of therapy.  (for more information go to the Request For Proposal tab on top)

Focus on IPAH (PPH)
Medical Research

The Cardiovascular Medical Research and Education Fund (CMREF) was created as a non-profit fund operated solely for charitable, scientific and educational purposes. The CMREF mission is the support of research to uncover the etiology and pathogenesis of idiopathic pulmonary arterial hypertension (IPAH, or PPH), in pursuit of the ultimate goal of its treatment and cure.

Specifically, the mission of the fund is to support education activities that will enhance the knowledge of pulmonary hypertension, and research projects that may help uncover the causes and pathogenesis of idiopathic pulmonary arterial hypertension (IPAH), in pursuit of the ultimate goal of its treatment and cure. 

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